Webb1 aug. 2000 · Propofol is widely used as an anesthetic agent for pediatric patients undergoing imaging studies and some therapeutic procedures . There have been isolated reports of its use in pediatric IAPs (7, 22) , but, to our knowledge, this is the largest series detailing its usefulness in this situation. WebbPropofol, in an intravenous dose of 0.5 mg/kg, administered at the end of a sevoflurane-nitrous oxide or desflurane-nitrous oxide anesthetic prolonged the times to awakening and orientation by 40-80% and 25-30%, respectively.
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One of propofol's most common side effects is pain on injection, especially in smaller veins. This pain arises from activation of the pain receptor, TRPA1, found on sensory nerves and can be mitigated by pretreatment with lidocaine. Less pain is experienced when infused at a slower rate in a large vein (antecubital fossa). Patients show considerable variability in their response to propofol, at times showing profound sedation with small doses[1]. WebbIntubation in the ICU is a high-risk procedure ( 1 ). Propofol, ketamine, and etomidate are common IV anesthetic agents used for induction of general anesthesia prior to rapid sequence intubation in critically ill patients ( 2 ). The choice between them is variable, complex, and multifactorial and not always adapted to the clinical condition. michael frank lawyer windsor
Propofol anesthesia - PubMed
Webb20 sep. 2024 · In many operations, propofol is used as an induction anesthetic and then isoflurane or desflurane as a follow on inhalation drug for moment-to-moment titration. Anesthetic binding agonizes the GABAA- and glycine-gated ion channels and potentiates their inhibitory activity. Webb6 apr. 2024 · propofol, anesthetic drug used to induce and maintain general anesthesia and to sedate patients for certain medical procedures. Propofol was first tested clinically in 1977. When administered by intravenous injection, it quickly induced anesthesia, with fast and smooth recovery afterward. WebbPropofol is also a reliable and safe anesthetic agent when used during induced cardiovascular and pulmonary-impaired conditions without surgery. The propofol … michael franklin whole earth