2024 Jph2 molecular weight

Jph2 molecular weight

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August undefined, 2024

Nettet21. mar. 2024 · Molecular mass: 74222 Da Protein existence level: PE1 Quaternary structure: Interacts with TRPC3 (PubMed:20095964). Interacts with BAG5 and HSPA8; … NettetAnti-JP-2 antibody (ab79071) Datasheet SDS Reviews ( 1) Submit a question References (3) Key features and details Rabbit polyclonal to JP-2 Suitable for: ELISA, WB Reacts …

Junctophilin-2 Expression Silencing Causes Cardiocyte …

Nettet1. sep. 2024 · Matsushita et al. (2007) noted that the JPH2 protein is composed of 6 predicted domains: MORN (membrane occupation and recognition nexus) motif region I … NettetConstruction of a sulfonation modification system for preparation of heparins having different molecular weights, and an application thereof, relating to the technical field of bioengineering. By means of synthetic biological technology and genetic engineering means, and by using Pichia pastoris GS115 as a starting strain, heparin synthesis … how a feeding tube works

Junctophilin-2 Expression Silencing Causes Cardiocyte Hypertrophy …

http://www.chem.cmu.edu/groups/berry/gcbmwd.pdf http://steeljis.com/jis_steel_datasheet.php?name_id=1194 Nettet9. aug. 2010 · Junctophilin-2 (JPH2) is a membrane-binding protein that plays a key role in the organization of the junctional membrane complex (JMC) in cardiac myocytes. JPH2 is believed to keep the plasma ... how many horsepower does a bugatti have

Emerging roles of junctophilin-2 in the heart and implications

JPH2 Protein Overview: Sequence, Structure, Function and Protein ...

NettetJPH2 is a hot spot for mutations linked to hypertrophic cardiomyopathy (HCM) ( 15 – 17 ), and repeats in JPH3 have been found to cause Huntington disease-like 2 (HDL-2) ( 18 ). In addition, cardiac stress results in activation of calpain, which cleaves JPH2 and drives heart failure progression ( 19 – 24 ). NettetThe molecular weight distribution (MWD) is conveniently characterized by either the number N(n) or weight W(n) of chains with n repeating units (e.g., a chain with molecular weight M = nm0 with m0 the molar weight of a repeating unit). The normalized functions N — (n) = N(n)/ΣN(n) (1) N — (n) = W(n)/ΣW(n) (2) respectively, are the number ... how a feed mill worksNettet30. mar. 2024 · ( G) mRNA expression levels for JPH2 and CAV3. ( H) Protein expression levels determined using JPH2 (sc-51313, Santa Cruz Biotechnology) and CAV3 (ab2912, Abcam) antibodies. n = 5 per group for G and H. * P < 0.05 and ** P < 0.01 vs. the euthermic group by Student’s t test. Open in viewer Increased Expression of JPH2 and … how many horsepower does a lamborghini have

"NettetUseful information about the protein provided by UniProt. [Junctophilin-2]: Membrane-binding protein that provides a structural bridge between the plasma membrane and the sarcopl asmic reticulum and is required for normal excitation-contraction coupling in cardiomyocytes 1. Provides a structural foundation for functional cross-talk between the ... " - Jph2 molecular weight

Jph2 molecular weight

JPH2 junctophilin 2 [Homo sapiens (human)] - Gene - NCBI

Nettet15. jun. 2014 · Mice with cardiac-specific shRNA-mediated knockdown of JPH2 were unable to form mature T-tubules within the first few weeks of life, while Bin1 levels remained unchanged. 14, 16 Conversely, T-tubule maturation occurred earlier in mice overexpressing JPH2 (Figure 1). 14 The disruption in maturation preferentially affected … Nettet2. mar. 2024 · JPH2 provided by HGNC Official Full Name junctophilin 2 provided by HGNC Primary source HGNC:HGNC:14202 See related Ensembl:ENSG00000149596 MIM:605267; AllianceGenome:HGNC:14202 Gene type ... Molecular Biology Databases. Bgee database; JPH2 gene expression; BioGPS; BioGPS;

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NettetTwelve 8-week-old male SD rats with a mean weight of 273.7 ± 3.2 g were randomized into two groups: six rats were subjected to saline (Double Crane Pharmaceutical Co. … NettetJPH2_ENST00000342272 Sequences You can see various sequences for this gene: cDNA (ENST00000372980.3) Protein (JPH2) Transcript and protein aligned …

Nettet9. aug. 2010 · Junctophilin-2 (JPH2) is a membrane-binding protein that plays a key role in the organization of the junctional membrane complex (JMC) in cardiac myocytes. NettetJPH2 Junctophilin-2: Membrane-binding protein that provides a structural bridge between the plasma membrane and the sarcoplasmic reticulum and is required for normal excitation-contraction coupling in cardiomyocytes. ... Molecular weight: 74,259 Da

NettetExpression of JPH2 protein in cerebral arteries was investigated using the Wes capillary electrophoresis immunoassay system (Fig. 1C). Protein lysates from whole cerebral arteries and hearts... Nettet18. apr. 2007 · Junctophilin-2 (JPH2) is a cardiac specific member of the junctophilins, a newly characterized family of junctional membrane complex proteins important in physically approximating the plasmalemmal L-type calcium channel and the sarcoplasmic reticulum ryanodine receptor for calcium-induced calcium release.

Nettet1. sep. 2024 · HGNC Approved Gene Symbol: JPH2 Cytogenetic location: 20q13.12 Genomic coordinates (GRCh38): 20:44,106,590-44,187,188 (from NCBI) Gene-Phenotype Relationships PheneGene Graphics TEXT Description how many horsepower does a bmw m3 haveNettet15. des. 2016 · Background: Junctophilin-2 (JPH2) is the primary structural protein for the coupling of transverse (T)-tubule associated cardiac L-type Ca channels and type-2 … how affective events theory worksNettetDownload scientific diagram Positive dose-dependent relationship between JPH2 expression and TT development. (A) Di-8-ANEPPS staining of ventricular myocytes isolated from aMHC-shJPH2 (knockdown ... how a fetus developsNettet18. okt. 2024 · Junctophilin 2, as junctional membrane complex (JMC) protein, is an important regulator of the cardiac SK channels RBFox2-miR-34a-Jph2 axis contributes to cardiac decompensation during heart failure loss of nuclear JP2NT function accelerates stress-induced development of hypertrophy and heart failure in mutant mice how many horsepower can a human produceNettet21. jun. 2024 · JPH2-null mice demonstrate embryonic lethality due to molecular failure of the JMC and ineffective Ca 2+-signaling needed to sustain EC coupling and cardiac … how many horse power 382ccNettetJPH2 Junctophilin-2: Membrane-binding protein that provides a structural bridge between the plasma membrane and the sarcoplasmic reticulum and is required for normal excitation-contraction coupling in cardiomyocytes. ... Molecular weight: 74,692 Da how a fever formsNettetKnow comprehensive JPH2 protein information including protein sequence, molecular weight, theoretical pI, structure, function and protein interaction. how many horsepower does a nascar have