Gleevec interactions with medications
Webimatinib apixaban. Applies to: Gleevec (imatinib) and apixaban. Imatinib may increase the blood levels of apixaban, which may result in a higher risk of bleeding complications. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. You should seek immediate medical attention if you experience ... Webimatinib oral (Gleevec Oral) Drug Interactions - Serious Interaction - RxList Medications known to have serious interactions with imatinib oral drug interactions checker …
Gleevec interactions with medications
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WebThe most frequently reported adverse reactions (>30%) are: Oedema Nausea Vomiting Muscle cramps Musculoskeletal pain Diarrhoea Fatigue Abdominal pain Skin changes Skin changes that often occur during treatment with imatinib include: Postoperative periorbital purpura Periorbital oedema and epiphora Drug-induced vitiligo WebWhat drug interactions occur with imatinib? Imatinib (Gleevec) is metabolized primarily by liver enzyme CYP3A4. Therefore, drugs also metabolized by this same enzyme may interact with imatinib, as well as drugs or other substances that increase (induce) or decrease (inhibit) the amount of this enzyme in the body.
WebApr 13, 2024 · The drug interaction between the hybrid compound and imatinib was studied using CompuSyn software. Drug synergism was determined with the help of the combination index (Figure 2a; Table 1) and isobologram (Figure 2b). Co-treatment of human leukemia cells with the hybrid and imatinib had a synergistic effect at all concentrations … WebMedications known to have contraindicated interactions with imatinib oral drug interactions checker contraindicated interactions for imatinib oral Brand Names …
WebThe main drug-drug interactions associated with imatinib include CYP3A4 Inhibitors/ Inducers CYP3A4 Inhibitors. Concomitant use of imatinib with CYP3A4 inhibitors may decrease metabolism and increase imatinib concentrations. 1 Examples include: protease inhibitors such as indinavir, lopinavir/ritonavir, saquinavir, telaprevir, boceprevir; azole … WebMay 23, 2024 · For instance, Gleevec is used to treat several additional types of cancer, compared with Sprycel. ... warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings ...
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Web7 DRUG INTERACTIONS 7.1 Agents Inducing CYP3A Metabolism 7.2 Agents Inhibiting CYP3A Metabolism 7.3 Interactions With Drugs Metabolized by CYP3A4 7.4 … bohler thyssen soldadurasWebApr 19, 2024 · GLEEVEC ® (imatinib mesylate) tablets have delivered efficacy and safety data backed by almost two decades of clinical use. 1 First approved by the FDA in 2001 1, the figures speak for themselves.. Over 15,000 published articles 2; Over 740 clinical trials 3; 5,000,000 packs distributed 4; GLEEVEC has a well-established safety profile. Thank … bohler thyssenWeb7 DRUG INTERACTIONS 7.1 Agents Inducing CYP3A Metabolism 7.2 Agents Inhibiting CYP3A Metabolism 7.3 Interactions With Drugs Metabolized by CYP3A4 7.4 Interactions With Drugs Metabolized by CYP2D6 8 USE IN SPECIFIC POPULATIONS 8.1 Pregnancy 8.2 Lactation 8.3 Females and Males of Reproductive Potential 8.4 Pediatric Use 8.5 … glo maps searchWebImatinib, sold under the brand names Gleevec and Glivec (both marketed worldwide by Novartis) among others, is an oral targeted therapy medication used to treat cancer. Imatinib is a small molecule inhibitor targeting multiple receptor tyrosine kinases such as CSF1R, ABL, c-KIT, FLT3, and PDGFR-β. Specifically, it is used for chronic … bohler thyssen utpWebimatinib apixaban. Applies to: Gleevec (imatinib) and apixaban. Imatinib may increase the blood levels of apixaban, which may result in a higher risk of bleeding complications. You … glomark625.wixsite.comWebMar 6, 2024 · Drug-Drug Interactions Last Updated: March 6, 2024 Ritonavir, a strong cytochrome P450 (CYP) 3A4 inhibitor and a P-glycoprotein inhibitor, is coadministered with nirmatrelvir to increase the blood concentration of nirmatrelvir, thereby making it effective against SARS-CoV-2. glomark black friday offersWebImatinib alcohol/food interactions There is 1 alcohol/food interaction with imatinib. Imatinib disease interactions There are 7 disease interactions with imatinib which … bohler thyssen welding usa